Bruce N. Ames 1997 Publications

370 Beckman, K. B. and Ames, B.N. (1997) Oxidants, Antioxidants, and Aging. In: Oxidative Stress and the Molecular Biology of Antioxidant Defenses, J. Scandalios, ed. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY), pp. 201-246. check for PDF

371 Gold, L. S., Slone, T. H., Manley, N. B., Garfinkel, G. B., Rohrbach, L. and Ames, B. N. (1997) The Carcinogenic Potency Database. In: Handbook of Carcinogenic Potency and Genotoxicity Databases, L. S. Gold and E. Zeiger, eds. (CRC Press, Boca Raton, FL), pp. 1-605. check for PDF

372 Gold, L. S., Slone, T. H. and Ames, B. N. (1997) The Carcinogenic Potency Database by Chemical. In: Handbook of Carcinogenic Potency and Genotoxicity Databases, L. S. Gold and E. Zeiger, eds. (CRC Press, Boca Raton, FL), pp. 621-660. check for PDF

373 Gold, L. S., Slone, T. H. and Ames, B. N. (1997) Overview and Update Analyses of the Carcinogenic Potency Database. In: Handbook of Carcinogenic Potency and Genotoxicity Databases, L. S. Gold and E. Zeiger, eds. (CRC Press, Boca Raton, FL), pp. 661-685. check for PDF

374 Woodall, A. A. and Ames, B. N. (1997) Nutritional Prevention of DNA Damage to Sperm and Consequent Risk Reduction in Birth Defects and Cancer in Offspring. In: Preventive Nutrition , A. Bendich and R. Deckelbaum, eds. (The Humana Press, Inc., Totowa, NJ), pp. 373-385. check for PDF

375 Liu, J., Yeo, H. C., Doniger, S. J., and Ames, B. N. (1997) Assay of Aldehydes from Lipid Peroxidation: Gas Chromatography-Mass Spectrometry Compared to Thibarbituric Acid. Anal. Biochem., 245, 161-166. check for PDF

376 Blount, B. C., Mack, M. M., Wehr, C., MacGregor, J., Hiatt, R., Wang, G., Wickramasinghe, S. N., Everson, R. B. and Ames, B. N. (1997) Folate Deficiency Causes Uracil Misincorporation into Human DNA and Chromosome Breakage: Implications for Cancer and Neuronal Damage. Proc. Natl. Acad. Sci. USA 94, 3290-3295. check for PDF

377 Christen, S., Woodall, A. A., Shigenaga, M. K., Southwell-Keely, P. T., Duncan, M. W. and Ames, B. N. (1997) gamma-tocopherol Traps Mutagenic Electrophiles such as NOx and Complements alpha-tocopherol: Physiological Implications. Proc. Natl. Acad. Sci. USA 94, 3217-3222. check for PDF 378 Shigenaga, M. K., Lee, H., Blount, B., Christen, S., Shigeno, E. T., Yip, H. and Ames, B. N. (1997) Inflammation and NOx-induced nitration: Assay for 3-nitrotyrosine by HPLC with Electrochemical Detection. Proc. Natl. Acad. Sci. USA 94:, 3211-3216. check for PDF

379 Hagen, T. M., Yowe, D. L., Bartholomew, J. C., Wehr, C. M., Do, K. L., Park, J.-Y. and Ames, B. N. (1997) Mitochondrial Decay in Hepatocytes from Old Rats: Membrane Potential Declines, Heterogeneity and Oxidants Increase. Proc. Natl. Acad. Sci. USA 94, 3064-3069. check for PDF

380 Woodall, A. A. and Ames, B. N. (1997) Diet and Oxidative Damage to DNA: The Importance of Ascorbate as an Antioxidant. In: Vitamin C in Health and Disease, L. Packer, ed. (Marcel Dekker, Inc., New York), pp. 193-203. check for PDF

381 Ames, B. N. and Gold, L. S. (1997) Environmental Pollution, Pesticides, and the Prevention of Cancer: Misconceptions. FASEB J. 11, 1041-1052. check for PDF

382 Koury, M. J., Horne, D. W., Brown, Z. A., Pietenpol, J. A., Blount, B. C., Ames, B. N., Hard, R. and Koury, S. T. (1997) Apoptosis of Late Stage Erythroblasts in Megaloblastic Anemia: The Association with DNA Damage and Macrocyte Production, Blood 89, 4617-4623. check for PDF

383 MacGregor, J. T., Wehr, C. M., Hiatt, R. A., Peters, B., Tucker, J. D., Langlois, R., Jacob, R. A., Jensen, R. H., Yager, J. W., Shigenaga, M. K., Frei, B., Eynon, B. P. and Ames, B. N. (1997) "Spontaneous" Genetic Damage in Man: Evaluation of Interindividual Variability, Relationship Among Markers of Damage, and Influence of Nutritional Status. Mutat. Res. 377, 125-135. check for PDF

384 Ames, B. N. and Gold, L. S. (1997) The Causes and Prevention of Cancer: Gaining Perspective. Environ. Health Perspect.. 105(Suppl 4), 865-873. check for PDF

385 Beckman, K. B. and Ames, B. N. (1997) Oxidative Decay of DNA., J. Biol. Chem. 272, 19633-19636. check for PDF

386 Ames, B. N. and Gold, L. S. (1997) Pollution, Pesticides, and Cancer: Misconceptions. In: What Risk?: Science, Politics and Public Health, R. Bate, ed. (Butterworth Heinemann, Oxford), pp. 173-190. check for PDF

387 Gold, L. S., Stern, B. R., Slone, T. H., Brown, J. P., Manley, N. B. and Ames, B. N. (1997) Pesticide Residues in Food: Investigation of Disparities in Cancer Risk Estimates. Cancer Lett. 117, 195-207. check for PDF

388 Ames, B.N. (1997) Il mito del rischio zero. Biblioteca della libert? 139, 17-23. check for PDF

389 Gold, L. S., Slone, T. H., and Ames, B. N. (1997) Prioritization of Possible Carcinogenic Hazards in Food. In: Food Chemical Risk Analysis, D. Tennant, ed. (Blackie Academic & Professional, London), pp. 267-295. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Dr. Ames current lecture abstract presented at CHORI, January 11, 2012 - Lecture Title: Vitamin and Mineral Inadequacy Accelerates Aging-Associated Diseases
Go to media page

Information on Juvenon

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