Bruce N. Ames 1994 Publications

323 Tribble, D. L., van den Berg, J. J. M., Motchnik, P. A., Ames, B. N., Lewis, D. M., Chait, A. and Krauss, R. M. (1994) Oxidative Susceptibility of Low Density Lipoprotein Subfractions is Related to their Ubiquinol-10 and alpha-tocopherol Content. Proc. Natl. Acad. Sci. USA 91, 1183-1187. check for PDF

324 Ames, B. N. (1994) The Assay of Endogenous Oxidative DNA Damage as Related to Aging. In: Practical Handbook of Human Biologic Age Determination, A. K. Balin, ed. (CRC Press, Inc., Boca Raton, FL), pp. 397-405. check for PDF

325 Chen, Q. and Ames, B. N. (1994) Senescence-Like Growth Arrest Induced by Hydrogen Peroxide in Human Diploid Fibroblast F65 Cells. Proc. Natl. Acad. Sci. USA 91, 4130-4134. check for PDF

326 Blount, B. C. and Ames, B. N. (1994) Analysis of Uracil in DNA by Gas Chromatography-Mass Spectrometry. Anal. Biochem. 219, 195-200. check for PDF

327 Douki, T. and Ames, B. N. (1994) An HPLC-EC Assay for 1,N2-Propano Adducts of 2'Deoxyguanosine with 4-Hydroxynonenal and other a,b-Unsaturated Aldehydes. Chem. Res. Toxicol. 7, 511-518. check for PDF

328 Fleming, S. E., Youngman, L. D. and Ames, B. N. (1994) Intestinal Cell Proliferation is Influenced by Intakes of Protein and Energy, Aflatoxin and Whole Body Radiation. Nutr. Cancer 22, 11-30. check for PDF 329 Yeo, H. C., Helbock, H. J., Chyu, D. W. and Ames, B. N. (1994) Assay of Malondialdehyde in Biological Fluids by Gas Chromatography-Mass Spectrometry. Anal. Biochem. 220, 391-396. check for PDF

330 Gold, L. S., Slone, T. H., Manley, N. B. and Ames, B. N. (1994) Heterocyclic Amines Formed By Cooking Food: Comparison of Bioassay Results with Other Chemicals in the Carcinogenic Potency Database. Cancer Lett. 83, 21-29. check for PDF

331 Ames, B. N., Shigenaga, M. K. and Hagen, T. M. (1994) Oxidants, Antioxidants, and the Degenerative Diseases of Aging. In: Biological Oxidants and Antioxidants, L. Packer and E. Cadenas, eds. (Hippokrates Verlag, Stuttgart, Germany), pp. 193-212. check for PDF

332 Cadet, J., Ravanat, J. L., Buchko, G. W., Yeo, H. C. and Ames, B. N. (1994) Singlet Oxygen DNA Damage: Chromatographic and Mass Spectrometric Analysis of Damage Products. In: Methods in Enzymology: Oxygen Radicals in Biological Systems, Part D, L. Packer, ed. (Academic Press, San Diego, CA), Vol. 234, pp. 79-88. check for PDF

333 Motchnik, P. A., Frei, B. and Ames, B. N. (1994) Measurement of Antioxidants in Human Blood Plasma. In: Methods in Enzymology: Oxygen Radicals in Biological Systems, Part D, L. Packer, ed. (Academic Press, San Diego, CA), Vol. 234, pp. 269-279. check for PDF

334 Shigenaga, M. K., Aboujaoude, E. N., Chen, Q. and Ames, B. N. (1994) Assays of Oxidative DNA Damage Biomarkers 8-Oxo-2'-deoxyguanosine and 8-Oxoguanine in Nuclear DNA and Biological Fluids by High-Performance Liquid Chromatography with Electrochemical Detection. In: Methods in Enzymology: Oxygen Radicals in Biological Systems, Part D, L. Packer, ed. (Academic Press, San Diego, CA), Vol. 234, 16-33. check for PDF

335 Ames, B. N. (1994) Foreword. In: Natural Antioxidants in Human Health and Disease, B. Frei, ed. (Academic Press, San Diego, CA), pp. xix-xxv. check for PDF

336 Shigenaga, M. K. and Ames, B. N. (1994) Oxidants and Mitochondrial Decay in Aging. In: Natural Antioxidants in Human Health and Disease, B. Frei, ed. (Academic Press, San Diego, CA), pp. 63-106. check for PDF

337 Sanchez-Ramos, J. R., …vervik, E. and Ames, B. N. (1994) A Marker of Oxyradical-Mediated DNA Damage (8-Hydroxy-2'Deoxyguanosine) is Increased in Nigro-Striatum of Parkinson's Disease Brain. Neurodegeneration 3, 197-204. check for PDF

338 Shigenaga, M. K., Hagen, T. M. and Ames, B. N. (1994) Oxidative Damage and Mitochondrial Decay in Aging. Proc. Natl. Acad. Sci. USA 91, 10771-10778. check for PDF

339 Gee, P., Maron, D. M. and Ames, B. N. (1994) Detection and Classification of Mutagens: A Set of Base-Specific Salmonella Tester Strains. Proc. Natl. Acad. Sci. USA 91, 11606-11610. check for PDF

340 Hagen, T. M., Huang, S., Curnutte, J., Fowler, P., Martinez, V., Wehr, C. M., Ames, B. N. and Chisari, F. V. (1994) Extensive Oxidative DNA Damage in Hepatocytes of Transgenic Mice with Chronic Active Hepatitis Destined to Develop Hepatocellular Carcinoma. Proc. Natl. Acad. Sci. USA 91, 12808-12812. check for PDF

341 Ames, B. N., Motchnik, P. A., Fraga, C. G., Shigenaga, M. K. and Hagen, T. M. (1994) Antioxidant Prevention of Birth Defects and Cancer. In: Male-Mediated Developmental Toxicity, D.R. Mattison and A. Olshan, eds. (Plenum Publishing Corp. New York, NY), pp. 243-260. check for PDF

342 Youngman, L. D., Shigenaga, M. K., Motchnik, P. and Ames, B. N. (1994) Effects of a Peroxisomal Proliferator (PP) on Plasma and Tissue Levels of Coenzyme Q9 (CoQ), Other Antioxidants, and Oxidative Damage to DNA (oxo8dG): Evidence that PP's Deplete Antioxidants and Increase Oxidative Damge to DNA. Molec. Aspects Med. 15, S131-141. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Dr. Ames current lecture abstract presented at CHORI, January 11, 2012 - Lecture Title: Vitamin and Mineral Inadequacy Accelerates Aging-Associated Diseases
Go to media page

Information on Juvenon

Please request all Juvenon related inquiries to Juvenon.